{"entity":{"id":"paper-stutman-science","kind":"paper","name":"Tumor development after 3-methylcholanthrene in immunologically deficient athymic-nude mice","aka":[],"tldr":"Paper cited by one term page, indexed on Europe PMC as PubMed record 4588620 and published in Science; the citing page links this DOI, which is how the record was matched.","summary":"Athymic-nude (nu/nu) mice and normal (nu/+) mice showed no differences in either latent period or incidence of local sarcomas or lung adenomas within 120 days after administration of 3-methylcholanthrene at birth. However, nu/nu mice were incapable of rejecting allogeneic skin grafts for the duration of the experiment. These results argue against an active role of thymus-dependent immunity as a surveillance mechanism preventing tumor development.\n\nIndexed on Europe PMC as PubMed record 4588620 (DOI 10.1126/science.183.4124.534). Matched by DOI alone: one term page cites this DOI among its external links (the pages are listed under Related), and this page was written so that the citation resolves inside OnCo. No figure has been checked by an editor.","asOf":"2026-09-22","links":[{"label":"Science 1974","url":"https://doi.org/10.1126/science.183.4124.534"},{"label":"PubMed","url":"https://pubmed.ncbi.nlm.nih.gov/4588620/"},{"label":"Europe PMC","url":"https://europepmc.org/article/MED/4588620"}],"tags":["europepmc-ingest"],"related":["immune-surveillance-immunoediting"],"cancers":[],"sections":[],"technologies":[],"targets":[],"drugs":[],"companies":[],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":["science"],"dependsOn":[],"notes":[],"journal":"Science","year":1974,"doi":"10.1126/science.183.4124.534","pmid":"4588620","authors":"Stutman O","paperType":"basic","findings":[],"whatItMeans":"One term page on OnCo cites this paper by its DOI; this record gives the citation a page of its own so a reader can follow it without leaving OnCo. Read the abstract above alongside the citing page listed under Related; the record was created automatically from the Europe PMC entry and its figures have not been checked by hand.","caveats":["Matched to the citing OnCo records by DOI alone; the summary reproduces the Europe PMC abstract and no figure has been verified against the full paper."]},"route":"/key-papers/paper-stutman-science/","neighbours":{"term":[{"id":"immune-surveillance-immunoediting","kind":"term","name":"Immune surveillance and cancer immunoediting","route":"/terms/immune-surveillance-immunoediting/"}],"journal":[{"id":"science","kind":"journal","name":"Science","route":"/journals/science/"}]}}