{"entity":{"id":"percist","kind":"term","name":"PERCIST (PET response criteria in solid tumours)","aka":["PERCIST","PERCIST 1.0","PET Response Criteria in Solid Tumors"],"tldr":"PERCIST judges response by how much sugar a tumour takes up on a PET scan rather than by its size, with a fall of 30% or more counting as a response.","summary":"Wahl and colleagues (Journal of Nuclear Medicine 2009) reviewed the limits of size-based criteria, which change little in effective treatment of lymphoma, sarcoma, liver cancer, mesothelioma and GIST, and proposed PERCIST 1.0. It measures lean-body-mass standardised uptake value in a fixed small region over the most active tumour, compares it with normal liver, treats the change as a continuous measure, requires a fall of 30% or more for response, and defers to RECIST 1.1 for tumours that do not take up FDG.","asOf":"2026-11-04","links":[{"label":"Wahl et al., From RECIST to PERCIST: evolving considerations for PET response criteria in solid tumors (J Nucl Med 2009)","url":"https://doi.org/10.2967/jnumed.108.057307"}],"tags":[],"related":["recist","eortc-pet-1999","deauville-score"],"cancers":[],"sections":[],"technologies":["fdg-pet","quantitative-imaging-biomarkers"],"targets":[],"drugs":[],"companies":[],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"category":"Endpoints"},"route":"/terms/percist/","neighbours":{"term":[{"id":"choi-criteria","kind":"term","name":"Choi criteria (GIST response on CT)","route":"/terms/choi-criteria/"},{"id":"deauville-score","kind":"term","name":"Deauville five-point scale","route":"/terms/deauville-score/"},{"id":"eortc-pet-1999","kind":"term","name":"EORTC PET response recommendations (1999)","route":"/terms/eortc-pet-1999/"},{"id":"recist","kind":"term","name":"RECIST","route":"/terms/recist/"}],"technology":[{"id":"fdg-pet","kind":"technology","name":"FDG PET","route":"/technologies/fdg-pet/"},{"id":"quantitative-imaging-biomarkers","kind":"technology","name":"Quantitative imaging biomarkers (RECIST, PERCIST, SUV, ADC)","route":"/technologies/quantitative-imaging-biomarkers/"}]}}