{"entity":{"id":"pf-06664178","kind":"drug","name":"PF-06664178","aka":[],"tldr":"This early TROP-2 antibody-drug conjugate was tested in a study that stopped before completing development.","summary":"NCT02122146 is terminated with 31 actual participants. The registry reports a business-related decision based on the overall results; this is a historical program, not a recruiting treatment opportunity.","status":"historic","asOf":"2026-10-06","links":[{"label":"ClinicalTrials.gov NCT02122146","url":"https://clinicaltrials.gov/study/NCT02122146"}],"tags":[],"related":[],"cancers":[],"sections":[],"technologies":[],"targets":["trop2"],"drugs":[],"companies":[],"institutions":[],"pathways":[],"terms":[],"trials":["nct02122146"],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"modality":"Antibody-drug conjugate","mechanism":"Anti-TROP2 antibody-drug conjugate.","approvals":[],"mechanismSteps":[],"toxicity":[],"access":[],"regulatoryEvents":[]},"route":"/drugs/pf-06664178/","neighbours":{"target":[{"id":"trop2","kind":"target","name":"TROP2","route":"/targets/trop2/"}],"trial":[{"id":"nct02122146","kind":"trial","name":"A Study Of PF-06664178 In Patients With Advanced Solid Tumors","route":"/trials/nct02122146/"}]}}