{"entity":{"id":"photonamic","kind":"company","name":"photonamic","aka":["photonamic GmbH & Co. KG","Photonamic"],"tldr":"photonamic is the small German company behind Gliolan (Gleolan), the drink of 5-aminolevulinic acid that makes glioma tissue glow pink under a surgical microscope so neurosurgeons can remove more of the tumour.","summary":"photonamic GmbH & Co. KG, founded in 2002 in Wedel near Hamburg, developed oral 5-aminolevulinic acid (Gliolan in Europe, Gleolan in the United States) for fluorescence-guided resection of high-grade glioma. Malignant glioma cells convert the drug into fluorescent protoporphyrin IX, and the randomised trial that led to European approval in 2007 showed more complete resections and longer progression-free survival; FDA approval followed in 2017 through its partner NX Development Corp. It leads phase 3 trials extending the approach, registered on ClinicalTrials.gov.","asOf":"2026-09-11","links":[{"label":"Official website","url":"http://www.photonamic.de"},{"label":"ClinicalTrials.gov: trials led by photonamic GmbH & Co. KG","url":"https://clinicaltrials.gov/search?lead=photonamic%20GmbH%20%26%20Co.%20KG"},{"label":"Wikidata","url":"https://www.wikidata.org/wiki/Q30269273"}],"tags":["ctgov-sponsor"],"related":[],"cancers":["glioblastoma"],"sections":[],"technologies":["fluorescence-guided-surgery"],"targets":[],"drugs":["aminolevulinic-acid"],"companies":[],"institutions":[],"pathways":[],"terms":["pivotal-trial","clinical-trial"],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"notes":[],"provenance":{"editedBy":"OnCo ingestion (ClinicalTrials.gov v2 + sponsor websites)","editedOn":"2026-09-11"},"hq":"Wedel","country":"DE","companyType":"pharma","website":"http://www.photonamic.de","founded":2002,"stage":"private-large","investors":[],"funding":[]},"route":"/companies/photonamic/","neighbours":{"cancer":[{"id":"glioblastoma","kind":"cancer","name":"Glioma & glioblastoma","route":"/cancers/glioblastoma/"}],"technology":[{"id":"fluorescence-guided-surgery","kind":"technology","name":"Fluorescence-guided surgery","route":"/technologies/fluorescence-guided-surgery/"}],"drug":[{"id":"aminolevulinic-acid","kind":"drug","name":"Aminolevulinic acid (topical, for photodynamic therapy)","route":"/drugs/aminolevulinic-acid/"}],"term":[{"id":"clinical-trial","kind":"term","name":"Clinical trial","route":"/terms/clinical-trial/"},{"id":"pivotal-trial","kind":"term","name":"Pivotal (registrational) trial","route":"/terms/pivotal-trial/"}]}}