{"entity":{"id":"ptk7","kind":"target","name":"PTK7","aka":[],"tldr":"PTK7 is a cell-surface protein being studied as an address for cancer-directed treatments.","summary":"AACR 2024 abstract 2616 describes PTK7 and TROP2 as the two antigens bound by BCG033. The cited antibody-drug conjugate evidence is from cell and xenograft models; it does not establish clinical benefit or a companion diagnostic.","asOf":"2026-10-06","links":[{"label":"AACR 2024 BCG033 abstract","url":"https://doi.org/10.1158/1538-7445.am2024-2616"},{"label":"HGNC PTK7 approved gene record","url":"https://rest.genenames.org/fetch/symbol/PTK7"}],"tags":[],"related":[],"cancers":[],"sections":[],"technologies":[],"targets":[],"drugs":[],"companies":[],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"symbol":"PTK7","role":[],"sources":[],"specificitySources":[],"hgnc":"HGNC:9618","ensembl":"ENSG00000112655","uniprot":"Q13308","entrez":"5754","biology":"Cell-surface antigen studied for binding and internalization of antibody-drug conjugates; the cited BCG033 abstract describes co-targeting with TROP2.","whereFound":[],"targetClass":"surface-antigen","prevalence":[]},"route":"/targets/ptk7/","neighbours":{"drug":[{"id":"bcg033","kind":"drug","name":"BCG033","route":"/drugs/bcg033/"}]}}