{"entity":{"id":"reach-galleri-medicare","kind":"trial","name":"REACH (Galleri in the Medicare population)","aka":["REACH study","GRAIL-MA-002","Galleri-Medicare"],"tldr":"A study of up to 50,000 older Americans on Medicare that gives them the Galleri test and compares how many cancers are found at stage IV.","summary":"REACH (NCT05673018) is a non-randomised interventional study sponsored by GRAIL, Inc. Its registry primary outcome is the incidence of stage IV cancers; it assesses real-world clinical impact, safety and test performance.\n\nThe registry record, read on 29 October 2026, gives its status as recruiting, with an estimated 50,000 participants, a start on 12 July 2024 and primary completion expected in September 2030.","status":"recruiting","asOf":"2026-10-29","links":[{"label":"ClinicalTrials.gov NCT05673018","url":"https://clinicaltrials.gov/study/NCT05673018"}],"tags":[],"related":[],"cancers":[],"sections":["early-detection"],"technologies":["mced","liquid-biopsy"],"targets":[],"drugs":["galleri"],"companies":["grail"],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"nct":"NCT05673018","phase":"not-applicable","setting":"People in the Medicare population in the United States, given Galleri in a comparative prospective cohort with enrolment meant to represent Medicare beneficiaries","sponsor":"GRAIL, Inc.","started":"2024-07-12","startedType":"actual","enrolled":50000,"enrolledBasis":"registry","outcomes":[]},"route":"/trials/reach-galleri-medicare/","neighbours":{"section":[{"id":"early-detection","kind":"section","name":"Early Detection & Screening","route":"/fronts/early-detection/"}],"technology":[{"id":"liquid-biopsy","kind":"technology","name":"Liquid biopsy (ctDNA)","route":"/technologies/liquid-biopsy/"},{"id":"mced","kind":"technology","name":"Multi-cancer early detection (MCED)","route":"/technologies/mced/"}],"drug":[{"id":"galleri","kind":"drug","name":"Galleri","route":"/drugs/galleri/"}],"company":[{"id":"grail","kind":"company","name":"GRAIL","route":"/companies/grail/"}]}}