{"entity":{"id":"stephen-freedland","kind":"person","name":"Stephen J. Freedland","aka":[],"tldr":"Los Angeles urologist who was lead author of EMBARK, the trial that established enzalutamide for men whose prostate cancer is returning fast after surgery or radiotherapy.","summary":"Stephen Freedland is a urologist at Cedars-Sinai in Los Angeles and the Durham VA. He was first author of the 2023 New England Journal of Medicine report of EMBARK, in which enzalutamide with or without leuprolide improved metastasis-free survival compared with leuprolide alone in men with high-risk biochemical recurrence of prostate cancer. His research also covers obesity, diet and outcomes in prostate cancer.","asOf":"2026-09-18","links":[],"tags":["prostate","trialist"],"related":[],"cancers":["prostate-bcr","prostate"],"sections":[],"technologies":[],"targets":[],"drugs":[],"companies":[],"institutions":["cedars-sinai-cancer"],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":["paper-embark-nejm-2023"],"journals":[],"dependsOn":[],"notes":[],"role":"Urologist, Cedars-Sinai Cancer","institutionId":"cedars-sinai-cancer","specialisms":["Prostate cancer","Biochemical recurrence","Diet and lifestyle in prostate cancer"],"profiles":[{"label":"PubMed","url":"https://pubmed.ncbi.nlm.nih.gov/?term=Freedland%5BAuthor%5D"}],"papers":[]},"route":"/people/stephen-freedland/","neighbours":{"cancer":[{"id":"prostate-bcr","kind":"cancer","name":"Biochemical recurrence of prostate cancer","route":"/cancers/prostate-bcr/"},{"id":"prostate","kind":"cancer","name":"Prostate cancer","route":"/cancers/prostate/"}],"institution":[{"id":"cedars-sinai-cancer","kind":"institution","name":"Cedars-Sinai Cancer","route":"/institutions/cedars-sinai-cancer/"}],"paper":[{"id":"paper-embark-nejm-2023","kind":"paper","name":"EMBARK: enzalutamide with or without leuprolide in high-risk biochemically recurrent prostate cancer","route":"/key-papers/paper-embark-nejm-2023/"}]}}