{"entity":{"id":"symbio-pharmaceuticals","kind":"company","name":"SymBio Pharmaceuticals","aka":["SymBio Pharmaceuticals Limited","シンバイオ製薬"],"tldr":"SymBio is a Tokyo company that brought bendamustine (Treakisym) to Japan for lymphoma and myeloma through the local trials it led, and now develops the antiviral brincidofovir for transplant complications.","summary":"SymBio Pharmaceuticals, founded in 2005 in Minato, Tokyo, in-licenses medicines for Japan and runs the domestic trials for approval. It won Japanese approval for bendamustine (Treakisym) in relapsed indolent lymphoma, mantle cell lymphoma and later first-line settings, and is developing brincidofovir for adenovirus infection after stem cell transplant. Its phase 3 trials are registered on ClinicalTrials.gov under SymBio as lead sponsor.","asOf":"2026-09-11","links":[{"label":"Official website","url":"http://www.symbiopharma.com"},{"label":"ClinicalTrials.gov: trials led by SymBio Pharmaceuticals Limited","url":"https://clinicaltrials.gov/search?lead=SymBio%20Pharmaceuticals%20Limited"},{"label":"Wikidata","url":"https://www.wikidata.org/wiki/Q38277748"}],"tags":["ctgov-sponsor"],"related":[],"cancers":["follicular-lymphoma","mantle-cell-lymphoma"],"sections":[],"technologies":[],"targets":[],"drugs":["bendamustine"],"companies":[],"institutions":[],"pathways":[],"terms":["pivotal-trial","clinical-trial"],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"notes":[],"provenance":{"editedBy":"OnCo ingestion (ClinicalTrials.gov v2 + sponsor websites)","editedOn":"2026-09-11"},"hq":"Tokyo","country":"JP","companyType":"pharma","website":"http://www.symbiopharma.com","founded":2005,"stage":"public","investors":[],"funding":[]},"route":"/companies/symbio-pharmaceuticals/","neighbours":{"cancer":[{"id":"follicular-lymphoma","kind":"cancer","name":"Follicular lymphoma","route":"/cancers/follicular-lymphoma/"},{"id":"mantle-cell-lymphoma","kind":"cancer","name":"Mantle cell lymphoma","route":"/cancers/mantle-cell-lymphoma/"}],"drug":[{"id":"bendamustine","kind":"drug","name":"Bendamustine","route":"/drugs/bendamustine/"}],"term":[{"id":"clinical-trial","kind":"term","name":"Clinical trial","route":"/terms/clinical-trial/"},{"id":"pivotal-trial","kind":"term","name":"Pivotal (registrational) trial","route":"/terms/pivotal-trial/"}]}}