{"entity":{"id":"thena-biotech","kind":"company","name":"Thena Biotech","aka":["Thena Biotech S.r.l."],"tldr":"Thena Biotech packs chemotherapy inside cages made from a natural human protein, ferritin, which tumour cells take up readily, to deliver the drug to cancer cells with fewer side effects.","summary":"Thena Biotech S.r.l., headquartered in Latina, Italy, is an early-clinical-stage company developing biotherapeutics based on human ferritin (HFt) nanocages, which it describes as natural nanocarriers with intrinsic tumour-targeting properties. Its TARGETED technology delivers chemotherapy drugs inside ferritin nanocages, and its BOOSTER technology delivers bioactive peptides to tumours using engineered ferritin. THE-0504, given intravenously, is in a single-centre phase 1 dose-escalation trial in solid tumours, with small cell lung cancer and colorectal cancer among the listed conditions (NCT07646106). Its first registered cancer trial, NCT07646106, was posted on ClinicalTrials.gov in June 2026.","asOf":"2026-10-29","links":[{"label":"Official website","url":"https://thenabiotech.com/"},{"label":"ClinicalTrials.gov: phase 1 trial of THE-0504 (NCT07646106)","url":"https://clinicaltrials.gov/study/NCT07646106"}],"tags":[],"related":[],"cancers":["sclc","colorectal"],"sections":["chemotherapy"],"technologies":["cytotoxic-chemotherapy"],"targets":[],"drugs":[],"companies":[],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":["Company website read on 29 October 2026. The payload of THE-0504 is not stated on the pages read. Founding year not stated. No financing found."],"hq":"Latina","country":"IT","companyType":"biotech","website":"https://thenabiotech.com/","stage":"startup","investors":[],"funding":[]},"route":"/companies/thena-biotech/","neighbours":{"cancer":[{"id":"colorectal","kind":"cancer","name":"Colorectal cancer","route":"/cancers/colorectal/"},{"id":"sclc","kind":"cancer","name":"Small-cell lung cancer","route":"/cancers/sclc/"}],"section":[{"id":"chemotherapy","kind":"section","name":"Chemotherapy","route":"/fronts/chemotherapy/"}],"technology":[{"id":"cytotoxic-chemotherapy","kind":"technology","name":"Cytotoxic chemotherapy","route":"/technologies/cytotoxic-chemotherapy/"}]}}