{"entity":{"id":"united-therapeutics","kind":"company","name":"United Therapeutics","aka":["United Therapeutics Corporation","Unither Pharmaceuticals"],"tldr":"United Therapeutics is a Maryland company known for pulmonary hypertension medicines that also makes dinutuximab (Unituxin), the anti-GD2 antibody that became standard for high-risk neuroblastoma in children.","summary":"United Therapeutics, founded in 1996 and headquartered in Silver Spring, Maryland, built its business on treatments for pulmonary arterial hypertension and now works on manufactured organs. In oncology it commercialises dinutuximab (Unituxin), the chimeric anti-GD2 antibody developed with the Children's Oncology Group and approved in 2015 for high-risk neuroblastoma after a phase 3 trial showed better event-free survival. ClinicalTrials.gov lists the company as lead sponsor of a phase 3 cancer trial.","asOf":"2026-09-11","links":[{"label":"Official website","url":"https://www.unither.com"},{"label":"ClinicalTrials.gov: trials led by United Therapeutics Corporation","url":"https://clinicaltrials.gov/search?lead=United%20Therapeutics%20Corporation"},{"label":"Wikidata","url":"https://www.wikidata.org/wiki/Q21071142"}],"tags":["ctgov-sponsor"],"related":[],"cancers":["neuroblastoma"],"sections":[],"technologies":[],"targets":[],"drugs":["dinutuximab"],"companies":[],"institutions":[],"pathways":[],"terms":["pivotal-trial","clinical-trial"],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"notes":[],"provenance":{"editedBy":"OnCo ingestion (ClinicalTrials.gov v2 + sponsor websites)","editedOn":"2026-09-11"},"hq":"Silver Spring, MD","country":"US","companyType":"biotech","website":"https://www.unither.com","founded":1996,"stage":"public","investors":[],"funding":[]},"route":"/companies/united-therapeutics/","neighbours":{"cancer":[{"id":"neuroblastoma","kind":"cancer","name":"Neuroblastoma (paediatric)","route":"/cancers/neuroblastoma/"}],"drug":[{"id":"dinutuximab","kind":"drug","name":"Dinutuximab (ch14.18) / dinutuximab beta","route":"/drugs/dinutuximab/"}],"term":[{"id":"clinical-trial","kind":"term","name":"Clinical trial","route":"/terms/clinical-trial/"},{"id":"pivotal-trial","kind":"term","name":"Pivotal (registrational) trial","route":"/terms/pivotal-trial/"}]}}