{"entity":{"id":"vicky-makker","kind":"person","name":"Vicky Makker","aka":[],"tldr":"New York oncologist who led KEYNOTE-775, the trial that established lenvatinib plus pembrolizumab for advanced endometrial cancer after chemotherapy.","summary":"Vicky Makker is a gynaecologic medical oncologist at Memorial Sloan Kettering Cancer Center. She led the phase 2 study and was first author of the 2022 New England Journal of Medicine report of KEYNOTE-775, the phase 3 trial in which lenvatinib plus pembrolizumab improved progression-free and overall survival compared with chemotherapy in advanced endometrial cancer after platinum-based therapy, including mismatch repair-proficient tumours.","asOf":"2026-09-18","links":[],"tags":["endometrial","gynaecological","immunotherapy","trialist"],"related":[],"cancers":["advanced-recurrent-endometrial-cancer","endometrial"],"sections":[],"technologies":[],"targets":[],"drugs":[],"companies":[],"institutions":["mskcc"],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":["paper-keynote-775-nejm-2022"],"journals":[],"dependsOn":[],"notes":[],"role":"Gynaecologic medical oncologist, Memorial Sloan Kettering Cancer Center","institutionId":"mskcc","specialisms":["Endometrial cancer","Immunotherapy combinations","Targeted therapy"],"profiles":[{"label":"PubMed","url":"https://pubmed.ncbi.nlm.nih.gov/?term=Makker%5BAuthor%5D"}],"papers":[]},"route":"/people/vicky-makker/","neighbours":{"cancer":[{"id":"advanced-recurrent-endometrial-cancer","kind":"cancer","name":"Advanced or recurrent endometrial cancer","route":"/cancers/advanced-recurrent-endometrial-cancer/"},{"id":"endometrial","kind":"cancer","name":"Endometrial cancer","route":"/cancers/endometrial/"}],"institution":[{"id":"mskcc","kind":"institution","name":"Memorial Sloan Kettering Cancer Center","route":"/institutions/mskcc/"}],"paper":[{"id":"paper-keynote-775-nejm-2022","kind":"paper","name":"KEYNOTE-775: lenvatinib plus pembrolizumab versus chemotherapy for previously treated advanced endometrial cancer","route":"/key-papers/paper-keynote-775-nejm-2022/"}]}}