{"entity":{"id":"vincere-firefighters-mced","kind":"trial","name":"Multi-cancer early detection in firefighters (Vincere Cancer Center)","aka":[],"tldr":"A US study testing two experimental multi-cancer tests, one on blood and urine sugars and one on blood proteins, in firefighters.","summary":"Multi-cancer early detection in firefighters (NCT05780957) is an observational study sponsored by Vincere Cancer Center with Elypta, Proteotype. Its primary outcomes are sensitivity, specificity and predictive values of Elypta's test in plasma, urine and both, and of Proteotype's protein test in plasma.\n\nThe registry record, read on 29 October 2026, gives its status as recruiting, with an estimated 2,000 participants, a start on 21 March 2023 and primary completion expected on 31 December 2026.","status":"recruiting","asOf":"2026-10-29","links":[{"label":"ClinicalTrials.gov NCT05780957","url":"https://clinicaltrials.gov/study/NCT05780957"}],"tags":[],"related":[],"cancers":[],"sections":["early-detection"],"technologies":["mced","liquid-biopsy"],"targets":[],"drugs":["gagome-mced-test"],"companies":["elypta"],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"nct":"NCT05780957","phase":"observational","setting":"Firefighters in the United States, giving blood and urine to test Elypta's and Proteotype's multi-cancer tests","sponsor":"Vincere Cancer Center with Elypta, Proteotype","started":"2023-03-21","startedType":"actual","enrolled":2000,"enrolledBasis":"registry","outcomes":[]},"route":"/trials/vincere-firefighters-mced/","neighbours":{"section":[{"id":"early-detection","kind":"section","name":"Early Detection & Screening","route":"/fronts/early-detection/"}],"technology":[{"id":"liquid-biopsy","kind":"technology","name":"Liquid biopsy (ctDNA)","route":"/technologies/liquid-biopsy/"},{"id":"mced","kind":"technology","name":"Multi-cancer early detection (MCED)","route":"/technologies/mced/"}],"drug":[{"id":"gagome-mced-test","kind":"drug","name":"Elypta GAGome multi-cancer test","route":"/drugs/gagome-mced-test/"}],"company":[{"id":"elypta","kind":"company","name":"Elypta","route":"/companies/elypta/"}]}}