{"entity":{"id":"walrinvax","kind":"drug","name":"Walrinvax (bivalent HPV vaccine, Yuxi Zerun)","aka":[],"tldr":"A bivalent HPV vaccine made in China by Yuxi Zerun Biotechnology, prequalified by WHO in August 2024.","summary":"WHO's list of prequalified vaccines carries Walrinvax (Yuxi Zerun Biotechnology Co., Ltd, regulated by China's National Medical Products Administration) as a bivalent human papillomavirus vaccine in a single-dose vial, prequalified on 2 August 2024. It is the later of the two vaccines regulated by China's NMPA on the list, after Cecolin.","status":"approved","asOf":"2026-11-04","links":[{"label":"WHO list of prequalified vaccines (CSV export)","url":"https://extranet.who.int/prequal/vaccines/prequalified/export?page&_format=csv"}],"tags":["preventive-vaccine","hpv-vaccine"],"related":["cecolin","hpv-bivalent-vaccine","who-prequalified-vaccines"],"cancers":[],"sections":["prevention"],"technologies":["hpv-vaccine"],"targets":[],"drugs":[],"companies":[],"institutions":[],"pathways":["oncogenic-viruses"],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"brand":"Walrinvax","modality":"Prophylactic vaccine (virus-like particles)","mechanism":"Recombinant HPV L1 capsid proteins form virus-like particles that train the immune system to make antibodies against the HPV types the vaccine covers.","approvals":[{"region":"WHO","year":2024,"indication":"WHO prequalification, bivalent HPV vaccine"}],"mechanismSteps":[],"toxicity":[],"access":[],"regulatoryEvents":[{"date":"2024-08-02","type":"approval","region":"WHO","note":"WHO prequalification (WHO list of prequalified vaccines)","source":"https://extranet.who.int/prequal/vaccines/prequalified/export?page&_format=csv"}]},"route":"/drugs/walrinvax/","neighbours":{"drug":[{"id":"cecolin","kind":"drug","name":"Cecolin (bivalent HPV vaccine, Xiamen Innovax)","route":"/drugs/cecolin/"},{"id":"hpv-bivalent-vaccine","kind":"drug","name":"HPV bivalent vaccine (types 16 and 18)","route":"/drugs/hpv-bivalent-vaccine/"}],"collection":[{"id":"who-prequalified-vaccines","kind":"collection","name":"WHO list of prequalified vaccines","route":"/collections/who-prequalified-vaccines/"}],"section":[{"id":"prevention","kind":"section","name":"Prevention & Risk","route":"/fronts/prevention/"}],"technology":[{"id":"hpv-vaccine","kind":"technology","name":"HPV & HBV vaccination","route":"/technologies/hpv-vaccine/"}],"pathway":[{"id":"oncogenic-viruses","kind":"pathway","name":"Oncogenic viruses","route":"/pathways/oncogenic-viruses/"}]}}