{"entity":{"id":"znf292","kind":"target","name":"ZNF292","aka":["zinc finger protein 292","Zinc finger protein 292","KIAA0530","ZFP292","bA393I2.3","Zn-15","Zn-16"],"tldr":"ZNF292 (Zinc finger protein 292) is a protein that switches other genes on and off. The public catalogues list it as a biomarker, and clinical evidence ties its variants to diagnosis, prognosis or drug response. Tied to Diffuse large B-cell lymphoma.","summary":"May be involved in transcriptional regulation.\n\nCIViC holds 1 clinical evidence item and 0 assertions across 1 variant.","asOf":"2026-09-23","links":[{"label":"HGNC HGNC:18410","url":"https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:18410"},{"label":"UniProt O60281","url":"https://www.uniprot.org/uniprotkb/O60281/entry"},{"label":"NCBI Gene 23036","url":"https://www.ncbi.nlm.nih.gov/gene/23036"},{"label":"Ensembl ENSG00000188994","url":"https://www.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000188994"}],"tags":["cancer-genes-wave"],"related":["civic"],"cancers":["dlbcl"],"sections":[],"technologies":[],"targets":[],"drugs":[],"companies":[],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":["Written by scripts/fetch-cancer-genes.ts from CIViC, Open Targets, IntOGen, HGNC and UniProt; the function text is UniProt's, condensed and in UK spelling. Roles: CIViC holds 1 clinical evidence items on its variants. Evidence tier \"clinical-evidence\" is the strongest of those signals.","Prevalence not recorded: none of the sources gives a positivity rate."],"provenance":{"editedBy":"scripts/fetch-cancer-genes.ts (CIViC, Open Targets, IntOGen, HGNC, UniProt)","editedOn":"2026-09-23"},"symbol":"ZNF292","role":["biomarker"],"evidenceTier":"clinical-evidence","sources":[{"label":"HGNC HGNC:18410","url":"https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:18410","note":"approved symbol, name, aliases, locus and cross-references (hgnc_complete_set.txt)"},{"label":"UniProt O60281","url":"https://www.uniprot.org/uniprotkb/O60281/entry","note":"protein name, function text, keywords and locations (REST API)"},{"label":"CIViC gene ZNF292","url":"https://civicdb.org/features/9236","note":"1 evidence items, 0 assertions, 1 variants; diseases: Diffuse Large B-cell Lymphoma (GraphQL API, CC0)"}],"hgnc":"HGNC:18410","ensembl":"ENSG00000188994","uniprot":"O60281","entrez":"23036","biology":"May be involved in transcriptional regulation. Location: Nucleus (UniProt). Locus 6q14.3 (HGNC).","whereFound":["Diffuse large B-cell lymphoma: CIViC evidence names this disease"],"targetClass":"transcription","prevalence":[]},"route":"/targets/znf292/","neighbours":{"collection":[{"id":"civic","kind":"collection","name":"CIViC","route":"/collections/civic/"}],"cancer":[{"id":"dlbcl","kind":"cancer","name":"Diffuse large B-cell lymphoma","route":"/cancers/dlbcl/"}]}}