# OnCo record 858-therapeutics (company). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/companies/858-therapeutics/>
  a schema:Organization ;
  onco:kind "company" ;
  schema:identifier "858-therapeutics" ;
  schema:name "858 Therapeutics"@en ;
  schema:alternateName "8five8 Therapeutics"@en ;
  schema:description "858 Therapeutics is developing a tablet that blocks PARG, a protein cancer cells use to repair damaged DNA, aiming at tumours that are already weak at DNA repair, such as some ovarian and breast cancers with BRCA changes. It is in its first human trial."@en ;
  schema:url <https://onco.cc/companies/858-therapeutics/>, <https://www.8five8tx.com/> ;
  schema:dateModified "2026-10-29"^^xsd:date ;
  schema:citation <https://www.8five8tx.com/>, <https://www.8five8tx.com/news> ;
  schema:addressCountry "US" ;
  onco:cancers <https://onco.cc/cancers/ovarian/>, <https://onco.cc/cancers/breast-cancer/>, <https://onco.cc/cancers/prostate/> ;
  onco:sections <https://onco.cc/fronts/targeted-therapy/> ;
  onco:technologies <https://onco.cc/technologies/synthetic-lethality-approaches/> ;
  onco:trials <https://onco.cc/trials/nct06395519/> .