# OnCo record aall0232 (trial). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/trials/aall0232/>
  a schema:MedicalTrial ;
  onco:kind "trial" ;
  schema:identifier "aall0232", "NCT00075725" ;
  schema:name "AALL0232"@en ;
  schema:alternateName "COG AALL0232"@en ;
  schema:description "AALL0232 showed that giving children with high-risk acute lymphoblastic leukaemia high doses of methotrexate with leucovorin rescue cured more of them than the older escalating schedule, and that the steroid dexamethasone helped children under ten but caused bone damage without benefit in older patients."@en ;
  schema:url <https://onco.cc/trials/aall0232/> ;
  schema:dateModified "2026-09-22"^^xsd:date ;
  schema:citation <https://clinicaltrials.gov/study/NCT00075725> ;
  onco:status "positive" ;
  onco:tag "soc-trials" ;
  onco:phase "3" ;
  onco:cancers <https://onco.cc/cancers/all-paediatric-high-risk/>, <https://onco.cc/cancers/all-leukemia/>, <https://onco.cc/cancers/leukaemia/> ;
  onco:technologies <https://onco.cc/technologies/cytotoxic-chemotherapy/> ;
  onco:drugs <https://onco.cc/drugs/methotrexate/>, <https://onco.cc/drugs/dexamethasone/>, <https://onco.cc/drugs/prednisone/>, <https://onco.cc/drugs/asparaginase/> ;
  onco:institutions <https://onco.cc/institutions/childrens-oncology-group/> ;
  onco:keyPapers <https://onco.cc/key-papers/paper-aall0232-larsen-jco-2016/> .