# OnCo record aall1231 (trial). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/trials/aall1231/>
  a schema:MedicalTrial ;
  onco:kind "trial" ;
  schema:identifier "aall1231", "NCT02112916" ;
  schema:name "AALL1231"@en ;
  schema:alternateName "COG AALL1231"@en ;
  schema:description "AALL1231 tried to improve treatment for T-cell leukaemia and lymphoma in children by adding bortezomib and by dropping routine radiotherapy to the brain; bortezomib clearly helped the lymphoma patients but not the whole group, and more than nine in ten children were spared cranial radiotherapy without more relapses."@en ;
  schema:url <https://onco.cc/trials/aall1231/> ;
  schema:dateModified "2026-09-22"^^xsd:date ;
  schema:citation <https://clinicaltrials.gov/study/NCT02112916> ;
  onco:status "mixed" ;
  onco:tag "soc-trials" ;
  onco:phase "3" ;
  onco:cancers <https://onco.cc/cancers/all-paediatric-high-risk/>, <https://onco.cc/cancers/all-leukemia/>, <https://onco.cc/cancers/leukaemia/> ;
  onco:technologies <https://onco.cc/technologies/cytotoxic-chemotherapy/> ;
  onco:drugs <https://onco.cc/drugs/bortezomib/>, <https://onco.cc/drugs/dexamethasone/>, <https://onco.cc/drugs/asparaginase/> ;
  onco:institutions <https://onco.cc/institutions/childrens-oncology-group/> ;
  onco:keyPapers <https://onco.cc/key-papers/paper-aall1231-bortezomib-t-all-teachey-jco-2022/> .