# OnCo record aall1331 (trial). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/trials/aall1331/>
  a schema:MedicalTrial ;
  onco:kind "trial" ;
  schema:identifier "aall1331", "NCT02101853" ;
  schema:name "AALL1331"@en ;
  schema:alternateName "COG AALL1331"@en ;
  schema:description "AALL1331 tested swapping blocks of harsh chemotherapy for the antibody blinatumomab in children whose leukaemia had come back; the antibody caused far fewer serious infections, more patients survived in the higher-risk group, and children whose relapse was in the bone marrow did better in the low-risk group too."@en ;
  schema:url <https://onco.cc/trials/aall1331/> ;
  schema:dateModified "2026-09-22"^^xsd:date ;
  schema:citation <https://clinicaltrials.gov/study/NCT02101853> ;
  onco:status "mixed" ;
  onco:tag "soc-trials" ;
  onco:phase "3" ;
  onco:cancers <https://onco.cc/cancers/all-paediatric-relapsed/>, <https://onco.cc/cancers/all-leukemia/>, <https://onco.cc/cancers/leukaemia/> ;
  onco:technologies <https://onco.cc/technologies/t-cell-engager/>, <https://onco.cc/technologies/bispecific-antibody/> ;
  onco:drugs <https://onco.cc/drugs/blinatumomab/> ;
  onco:institutions <https://onco.cc/institutions/childrens-oncology-group/> ;
  onco:keyPapers <https://onco.cc/key-papers/paper-aall1331-brown-jama-2021/>, <https://onco.cc/key-papers/paper-aall1331-low-risk-hogan-jco-2023/> .