# OnCo record abc-02 (trial). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/trials/abc-02/>
  a schema:MedicalTrial ;
  onco:kind "trial" ;
  schema:identifier "abc-02", "NCT00262769" ;
  schema:name "ABC-02"@en ;
  schema:description "ABC-02 was the 2010 UK trial that gave bile duct cancer its first standard chemotherapy: 410 patients with advanced biliary tract cancer were randomised to gemcitabine plus cisplatin or gemcitabine alone, and the doublet lengthened life and delayed progression. It stayed the control arm for every first-line trial for more than a decade."@en ;
  schema:url <https://onco.cc/trials/abc-02/> ;
  schema:dateModified "2026-09-07"^^xsd:date ;
  schema:citation <https://www.nejm.org/doi/full/10.1056/NEJMoa0908721>, <https://clinicaltrials.gov/study/NCT00262769>, <https://www.isrctn.com/ISRCTN82956140> ;
  onco:status "positive" ;
  onco:phase "3" ;
  schema:startDate "2005-05" ;
  onco:cancers <https://onco.cc/cancers/cholangiocarcinoma/>, <https://onco.cc/cancers/gallbladder/>, <https://onco.cc/cancers/biliary-tract-cancer/> ;
  onco:technologies <https://onco.cc/technologies/cytotoxic-chemotherapy/>, <https://onco.cc/technologies/platinum/> ;
  onco:drugs <https://onco.cc/drugs/gemcitabine-cisplatin/> ;
  onco:institutions <https://onco.cc/institutions/cruk/> ;
  onco:people <https://onco.cc/people/juan-valle/> ;
  onco:keyPapers <https://onco.cc/key-papers/paper-abc-02-gemcitabine-cisplatin-nejm-2010/> .