# OnCo record abemaciclib (drug). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix owl: <http://www.w3.org/2002/07/owl#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/drugs/abemaciclib/>
  a schema:Drug ;
  onco:kind "drug" ;
  schema:identifier "abemaciclib" ;
  schema:name "Abemaciclib"@en ;
  schema:description "Abemaciclib was the first CDK4/6 inhibitor approved after surgery for high-risk hormone-positive breast cancer."@en ;
  schema:url <https://onco.cc/drugs/abemaciclib/> ;
  schema:dateModified "2026-09-04"^^xsd:date ;
  schema:sameAs <https://en.wikipedia.org/wiki/Abemaciclib> ;
  owl:sameAs <http://www.wikidata.org/entity/Q23901483> ;
  schema:citation <https://dailymed.nlm.nih.gov/dailymed/search.cfm?query=Abemaciclib> ;
  onco:status "approved" ;
  onco:modality "Small-molecule CDK4/6 inhibitor" ;
  schema:alternateName "Verzenio" ;
  onco:approval "US 2017: HR+/HER2- advanced breast cancer", "US 2021: Adjuvant high-risk node-positive HR+/HER2- early breast cancer" ;
  onco:cancers <https://onco.cc/cancers/breast-hr-positive/>, <https://onco.cc/cancers/hr-positive-early-high-risk/>, <https://onco.cc/cancers/hr-positive-metastatic-post-cdk46/> ;
  onco:technologies <https://onco.cc/technologies/cdk46-inhibitor/> ;
  onco:targets <https://onco.cc/targets/cdk4-6/> ;
  onco:companies <https://onco.cc/companies/eli-lilly/> ;
  onco:trials <https://onco.cc/trials/monarche/>, <https://onco.cc/trials/nct02152631/>, <https://onco.cc/trials/nct03706365/>, <https://onco.cc/trials/nct05735080/>, <https://onco.cc/trials/nct06810544/>, <https://onco.cc/trials/nct05867251/>, <https://onco.cc/trials/nct05768139/>, <https://onco.cc/trials/nct07100106/>, <https://onco.cc/trials/nct06413706/>, <https://onco.cc/trials/nct06065748/>, <https://onco.cc/trials/nct05440786/>, <https://onco.cc/trials/nct02763566/>, <https://onco.cc/trials/nct05999994/>, <https://onco.cc/trials/nct05696626/>, <https://onco.cc/trials/nct07002177/>, <https://onco.cc/trials/nct02107703/>, <https://onco.cc/trials/nct05548127/>, <https://onco.cc/trials/nct02747004/>, <https://onco.cc/trials/nct05288166/>, <https://onco.cc/trials/nct04862663/>, <https://onco.cc/trials/nct06380751/>, <https://onco.cc/trials/nct06760637/>, <https://onco.cc/trials/nct05386108/>, <https://onco.cc/trials/nct05573126/>, <https://onco.cc/trials/nct07605728/> .