# OnCo record abiraterone (drug). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix owl: <http://www.w3.org/2002/07/owl#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/drugs/abiraterone/>
  a schema:Drug ;
  onco:kind "drug" ;
  schema:identifier "abiraterone" ;
  schema:name "Abiraterone acetate"@en ;
  schema:alternateName "Abiraterone"@en, "Zytiga (generic)" ;
  schema:description "Abiraterone is a pill that shuts down testosterone production everywhere, including inside the tumour. Discovered at the Institute of Cancer Research, now generic and used from the first metastatic diagnosis."@en ;
  schema:url <https://onco.cc/drugs/abiraterone/> ;
  schema:dateModified "2026-09-06"^^xsd:date ;
  schema:sameAs <https://en.wikipedia.org/wiki/Abiraterone_acetate> ;
  owl:sameAs <http://www.wikidata.org/entity/Q27888393> ;
  schema:citation <https://dailymed.nlm.nih.gov/dailymed/search.cfm?query=Abiraterone%20acetate>, <https://www.nice.org.uk/guidance/ta1110>, <https://www.nice.org.uk/guidance/ta387>, <https://www.nice.org.uk/guidance/ta259> ;
  onco:status "approved" ;
  onco:modality "Small-molecule CYP17A1 inhibitor" ;
  onco:approval "US 2011: mCRPC after docetaxel", "US 2012: mCRPC pre-chemotherapy", "US 2018: High-risk mHSPC (LATITUDE)" ;
  onco:cancers <https://onco.cc/cancers/prostate/>, <https://onco.cc/cancers/prostate-mhspc/>, <https://onco.cc/cancers/prostate-mcrpc/>, <https://onco.cc/cancers/prostate-high-risk/> ;
  onco:technologies <https://onco.cc/technologies/androgen-deprivation/> ;
  onco:targets <https://onco.cc/targets/androgen-receptor/> ;
  onco:companies <https://onco.cc/companies/johnson-johnson/> ;
  onco:institutions <https://onco.cc/institutions/icr-london/>, <https://onco.cc/institutions/royal-marsden/> ;
  onco:pathways <https://onco.cc/pathways/ar-signaling/> ;
  onco:terms <https://onco.cc/terms/prostate-uk-drug-approvals/> ;
  onco:trials <https://onco.cc/trials/latitude/>, <https://onco.cc/trials/stampede/>, <https://onco.cc/trials/peace-1/>, <https://onco.cc/trials/propel/>, <https://onco.cc/trials/magnitude/>, <https://onco.cc/trials/capitello-281/>, <https://onco.cc/trials/nct03348670/>, <https://onco.cc/trials/nct06520345/>, <https://onco.cc/trials/nct03706365/>, <https://onco.cc/trials/nct07213674/>, <https://onco.cc/trials/nct04446117/>, <https://onco.cc/trials/nct05171816/>, <https://onco.cc/trials/nct07611110/>, <https://onco.cc/trials/nct04691804/>, <https://onco.cc/trials/nct05422911/>, <https://onco.cc/trials/nct07287150/>, <https://onco.cc/trials/nct07230106/>, <https://onco.cc/trials/nct02960022/>, <https://onco.cc/trials/nct05367440/>, <https://onco.cc/trials/nct06991556/>, <https://onco.cc/trials/nct07005154/>, <https://onco.cc/trials/nct02861573/>, <https://onco.cc/trials/nct05067140/>, <https://onco.cc/trials/nct07198633/>, <https://onco.cc/trials/nct07190300/>, <https://onco.cc/trials/nct07553988/>, <https://onco.cc/trials/nct02257736/>, <https://onco.cc/trials/nct03431350/>, <https://onco.cc/trials/nct04497844/> .