# OnCo record acns0121 (trial). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/trials/acns0121/>
  a schema:MedicalTrial ;
  onco:kind "trial" ;
  schema:identifier "acns0121", "NCT00027846" ;
  schema:name "ACNS0121"@en ;
  schema:alternateName "COG ACNS0121"@en ;
  schema:description "ACNS0121 showed that focused radiotherapy to the tumour bed straight after surgery cures most children with ependymoma, including those under three who used to be denied radiotherapy, and that children whose tumour could not be fully removed do far worse even with chemotherapy and a second operation."@en ;
  schema:url <https://onco.cc/trials/acns0121/> ;
  schema:dateModified "2026-09-22"^^xsd:date ;
  schema:citation <https://clinicaltrials.gov/study/NCT00027846> ;
  onco:status "positive" ;
  onco:tag "soc-trials" ;
  onco:phase "2" ;
  onco:cancers <https://onco.cc/cancers/ependymoma/>, <https://onco.cc/cancers/brain-tumours/>, <https://onco.cc/cancers/childhood-cancers/> ;
  onco:technologies <https://onco.cc/technologies/imrt-igrt/>, <https://onco.cc/technologies/cytotoxic-chemotherapy/> ;
  onco:drugs <https://onco.cc/drugs/carboplatin/>, <https://onco.cc/drugs/cyclophosphamide/>, <https://onco.cc/drugs/etoposide/>, <https://onco.cc/drugs/vincristine/> ;
  onco:institutions <https://onco.cc/institutions/childrens-oncology-group/> ;
  onco:keyPapers <https://onco.cc/key-papers/paper-acns0121-ependymoma-conformal-radiotherapy-merchant-jco-2019/> .