# OnCo record acns0332 (trial). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/trials/acns0332/>
  a schema:MedicalTrial ;
  onco:kind "trial" ;
  schema:identifier "acns0332", "NCT00392327" ;
  schema:name "COG ACNS0332"@en ;
  schema:alternateName "ACNS0332"@en ;
  schema:description "ACNS0332 found that giving carboplatin alongside radiotherapy improved survival for children with the most aggressive group 3 medulloblastomas, while isotretinoin, tested in the same trial, did nothing and was dropped."@en ;
  schema:url <https://onco.cc/trials/acns0332/> ;
  schema:dateModified "2026-09-17"^^xsd:date ;
  schema:citation <https://clinicaltrials.gov/study/NCT00392327> ;
  onco:status "mixed" ;
  onco:tag "subtype-trials" ;
  onco:phase "3" ;
  onco:cancers <https://onco.cc/cancers/medulloblastoma-group-3-4/>, <https://onco.cc/cancers/medulloblastoma/> ;
  onco:drugs <https://onco.cc/drugs/carboplatin/>, <https://onco.cc/drugs/vincristine/>, <https://onco.cc/drugs/cisplatin/>, <https://onco.cc/drugs/cyclophosphamide/> ;
  onco:people <https://onco.cc/people/sarah-leary/> ;
  onco:keyPapers <https://onco.cc/key-papers/paper-acns0332-leary-jama-oncol-2021/> .