# OnCo record act-ii (trial). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/trials/act-ii/>
  a schema:MedicalTrial ;
  onco:kind "trial" ;
  schema:identifier "act-ii" ;
  schema:name "ACT II"@en ;
  schema:description "ACT II, the largest anal cancer trial, confirmed mitomycin-fluorouracil chemoradiation as the standard, showed that swapping in cisplatin or adding maintenance chemotherapy gave nothing, and taught doctors to wait six months before judging response."@en ;
  schema:url <https://onco.cc/trials/act-ii/> ;
  schema:dateModified "2026-09-17"^^xsd:date ;
  schema:citation <https://www.isrctn.com/ISRCTN26715889>, <https://doi.org/10.1016/S1470-2045(13)70086-X> ;
  onco:status "positive" ;
  onco:tag "radiation-wave4" ;
  onco:phase "3" ;
  onco:cancers <https://onco.cc/cancers/anal/>, <https://onco.cc/cancers/localised-anal-cancer/> ;
  onco:technologies <https://onco.cc/technologies/imrt-igrt/>, <https://onco.cc/technologies/radiosensitisers/> ;
  onco:drugs <https://onco.cc/drugs/mitomycin/>, <https://onco.cc/drugs/cisplatin/>, <https://onco.cc/drugs/fluorouracil/> ;
  onco:terms <https://onco.cc/terms/chemoradiation/> .