# OnCo record actinium-225-supply (technology). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/technologies/actinium-225-supply/>
  a schema:MedicalTherapy ;
  onco:kind "technology" ;
  schema:identifier "actinium-225-supply" ;
  schema:name "Actinium-225 supply: thorium stocks, accelerators and radium targets"@en ;
  schema:description "Actinium-225 is the alpha-emitting atom behind the most promising next wave of radioligand therapies, and there is not enough of it. Almost all of it used to come from one decaying stock of thorium in a US national laboratory. New routes use accelerators and old radium."@en ;
  schema:url <https://onco.cc/technologies/actinium-225-supply/> ;
  schema:dateModified "2026-09-17"^^xsd:date ;
  schema:citation <https://www.isotopes.gov/>, <https://en.wikipedia.org/wiki/Actinium-225> ;
  onco:status "phase-3" ;
  onco:tag "manufacturing-wave" ;
  onco:cancers <https://onco.cc/cancers/prostate/>, <https://onco.cc/cancers/neuroendocrine/> ;
  onco:sections <https://onco.cc/fronts/radiopharma/> ;
  onco:technologies <https://onco.cc/technologies/therapy-isotope-supply-chain/>, <https://onco.cc/technologies/targeted-alpha-therapy/>, <https://onco.cc/technologies/cyclotron-isotope-production/>, <https://onco.cc/technologies/research-reactor-isotope-production/>, <https://onco.cc/technologies/radiopharmaceutical-gmp-release/>, <https://onco.cc/technologies/alpha-nanogenerators/> ;
  onco:drugs <https://onco.cc/drugs/ryz101/>, <https://onco.cc/drugs/ac225-psma/>, <https://onco.cc/drugs/fpi-2265/>, <https://onco.cc/drugs/alphamedix/> ;
  onco:companies <https://onco.cc/companies/terrapower-isotopes/>, <https://onco.cc/companies/eckert-ziegler/>, <https://onco.cc/companies/northstar-medical-radioisotopes/>, <https://onco.cc/companies/nusano/>, <https://onco.cc/companies/rayzebio/>, <https://onco.cc/companies/bms/>, <https://onco.cc/companies/bayer/>, <https://onco.cc/companies/novartis/>, <https://onco.cc/companies/astrazeneca/>, <https://onco.cc/companies/orano-med/>, <https://onco.cc/companies/itm/> ;
  onco:bottlenecks <https://onco.cc/bottlenecks/b-manufacturing-cell-therapy/> .