# OnCo record action-dmg (trial). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/trials/action-dmg/>
  a schema:MedicalTrial ;
  onco:kind "trial" ;
  schema:identifier "action-dmg", "NCT05580562" ;
  schema:name "ACTION"@en ;
  schema:description "ACTION is the first placebo-controlled phase 3 trial ever run in diffuse midline glioma, the childhood brain-stem tumour that radiotherapy alone has never cured. It asks whether taking dordaviprone after radiotherapy lengthens life."@en ;
  schema:url <https://onco.cc/trials/action-dmg/> ;
  schema:dateModified "2026-09-10"^^xsd:date ;
  schema:citation <https://clinicaltrials.gov/study/NCT05580562>, <https://www.jazzpharma.com> ;
  onco:status "recruiting" ;
  onco:tag "nci-coverage", "paediatric", "cns" ;
  onco:phase "3" ;
  schema:startDate "2023-01-23" ;
  onco:cancers <https://onco.cc/cancers/dipg-dmg/> ;
  onco:drugs <https://onco.cc/drugs/dordaviprone/> ;
  onco:companies <https://onco.cc/companies/jazz/> ;
  onco:terms <https://onco.cc/terms/h3k27m/>, <https://onco.cc/terms/race-for-children-act/> ;
  onco:bottlenecks <https://onco.cc/bottlenecks/b-brain-delivery/>, <https://onco.cc/bottlenecks/b-rare-cancers/> .