# OnCo record acvr1b (target). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/targets/acvr1b/>
  a schema:BioChemEntity ;
  onco:kind "target" ;
  schema:identifier "acvr1b" ;
  schema:name "ACVR1B"@en ;
  schema:alternateName "activin A receptor type 1B"@en, "Activin receptor type-1B"@en, "ALK4"@en, "SKR2"@en, "ActRIB"@en, "ACVRLK4"@en, "ACVR1B" ;
  schema:description "ACVR1B (Activin receptor type-1B) is a protein kinase, an enzyme that switches other proteins on by adding phosphate groups. The public catalogues list it as a tumour suppressor, and it is called a cancer driver by mutation analysis of patient cohorts. Tied to Pancreatic ductal adenocarcinoma, Colorectal cancer, Breast cancer and 4 more."@en ;
  schema:url <https://onco.cc/targets/acvr1b/> ;
  schema:dateModified "2026-09-23"^^xsd:date ;
  schema:citation <https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:172>, <https://www.uniprot.org/uniprotkb/P36896/entry>, <https://www.ncbi.nlm.nih.gov/gene/91>, <https://www.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000135503> ;
  onco:tag "cancer-genes-wave" ;
  onco:targetClass "kinase" ;
  schema:sameAs <https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:172>, <https://www.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000135503>, <https://www.uniprot.org/uniprotkb/P36896/entry>, <https://www.ncbi.nlm.nih.gov/gene/91> ;
  onco:related <https://onco.cc/collections/open-targets/>, <https://onco.cc/collections/intogen/> ;
  onco:cancers <https://onco.cc/cancers/pancreatic/>, <https://onco.cc/cancers/colorectal/>, <https://onco.cc/cancers/breast-cancer/>, <https://onco.cc/cancers/skin-cancer/>, <https://onco.cc/cancers/lung-cancer/>, <https://onco.cc/cancers/nsclc/>, <https://onco.cc/cancers/melanoma/> .