# OnCo record acvr2a (target). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/targets/acvr2a/>
  a schema:BioChemEntity ;
  onco:kind "target" ;
  schema:identifier "acvr2a" ;
  schema:name "ACVR2A"@en ;
  schema:alternateName "activin A receptor type 2A"@en, "Activin receptor type-2A"@en, "ACTRII"@en, "ACVR2"@en, "ACVR2A" ;
  schema:description "ACVR2A (Activin receptor type-2A) is a protein kinase, an enzyme that switches other proteins on by adding phosphate groups. The public catalogues list it as an oncogene driver and a tumour suppressor, and it is called a cancer driver by mutation analysis of patient cohorts. Tied to Colorectal cancer, Hepatocellular carcinoma, Pancreatic ductal adenocarcinoma and 4 more."@en ;
  schema:url <https://onco.cc/targets/acvr2a/> ;
  schema:dateModified "2026-09-23"^^xsd:date ;
  schema:citation <https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:173>, <https://www.uniprot.org/uniprotkb/P27037/entry>, <https://www.ncbi.nlm.nih.gov/gene/92>, <https://www.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000121989> ;
  onco:tag "cancer-genes-wave" ;
  onco:targetClass "kinase" ;
  schema:sameAs <https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:173>, <https://www.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000121989>, <https://www.uniprot.org/uniprotkb/P27037/entry>, <https://www.ncbi.nlm.nih.gov/gene/92> ;
  onco:related <https://onco.cc/collections/open-targets/>, <https://onco.cc/collections/intogen/> ;
  onco:cancers <https://onco.cc/cancers/colorectal/>, <https://onco.cc/cancers/hcc/>, <https://onco.cc/cancers/pancreatic/>, <https://onco.cc/cancers/gastric/>, <https://onco.cc/cancers/prostate/>, <https://onco.cc/cancers/endometrial/>, <https://onco.cc/cancers/cutaneous-scc/> .