# OnCo record ada (target). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/targets/ada/>
  a schema:BioChemEntity ;
  onco:kind "target" ;
  schema:identifier "ada" ;
  schema:name "Adenosine deaminase (ADA)"@en ;
  schema:description "Adenosine deaminase is an enzyme that breaks down adenosine and deoxyadenosine; blocking it with pentostatin poisons lymphocytes, which is why the drug works in hairy cell leukaemia and some T-cell cancers."@en ;
  schema:url <https://onco.cc/targets/ada/> ;
  schema:dateModified "2026-09-04"^^xsd:date ;
  schema:sameAs <https://en.wikipedia.org/wiki/Adenosine_deaminase>, <https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:186>, <https://www.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000196839>, <https://www.uniprot.org/uniprotkb/P00813/entry>, <https://www.ncbi.nlm.nih.gov/gene/100> ;
  schema:citation <https://www.uniprot.org/uniprotkb/P00813/entry>, <https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:186> ;
  schema:alternateName "ADA" ;
  onco:targetClass "enzyme" ;
  onco:firstDescribed "1983"^^xsd:gYear ;
  onco:cancers <https://onco.cc/cancers/hairy-cell-leukemia/>, <https://onco.cc/cancers/cll/> ;
  onco:drugs <https://onco.cc/drugs/pentostatin/> ;
  onco:terms <https://onco.cc/terms/apoptosis/> .