# OnCo record adaptive-therapy-dynamics (technology). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/technologies/adaptive-therapy-dynamics/>
  a schema:MedicalTherapy ;
  onco:kind "technology" ;
  schema:identifier "adaptive-therapy-dynamics" ;
  schema:name "Adaptive therapy (evolution-based dosing)"@en ;
  schema:description "Instead of hitting a tumour as hard as possible, adaptive therapy gives just enough drug to keep it in check and stops when it shrinks, so drug-sensitive cells survive to compete with resistant ones. A pilot trial in prostate cancer roughly doubled the time to progression on abiraterone."@en ;
  schema:url <https://onco.cc/technologies/adaptive-therapy-dynamics/> ;
  schema:dateModified "2026-09-17"^^xsd:date ;
  schema:citation <https://doi.org/10.1038/s41467-017-01968-5>, <https://doi.org/10.1158/0008-5472.CAN-08-3658> ;
  onco:status "emerging" ;
  onco:tag "mathematical-model" ;
  onco:cancers <https://onco.cc/cancers/prostate/>, <https://onco.cc/cancers/melanoma/> ;
  onco:sections <https://onco.cc/fronts/ai-computation/>, <https://onco.cc/fronts/drug-discovery/> ;
  onco:technologies <https://onco.cc/technologies/clonal-evolution-tracking/>, <https://onco.cc/technologies/drug-resistance-dynamics/> ;
  onco:drugs <https://onco.cc/drugs/abiraterone/> ;
  onco:keyPapers <https://onco.cc/key-papers/paper-zhang-nat-commun/>, <https://onco.cc/key-papers/paper-gatenby-cancer-res/> .