# OnCo record adc-after-adc-caution (pairing). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/pairings/adc-after-adc-caution/>
  a schema:MedicalTherapy ;
  onco:kind "pairing" ;
  schema:identifier "adc-after-adc-caution" ;
  schema:name "Caution: TOP1 ADC immediately after TOP1 ADC"@en ;
  schema:description "Giving a second ADC with the same kind of payload straight after the first often does not work well."@en ;
  schema:url <https://onco.cc/pairings/adc-after-adc-caution/> ;
  schema:dateModified "2026-09-04"^^xsd:date ;
  schema:citation <https://doi.org/10.1200/jco.2023.41.16_suppl.1022> ;
  onco:cancers <https://onco.cc/cancers/tnbc/>, <https://onco.cc/cancers/breast-hr-positive/> ;
  onco:drugs <https://onco.cc/drugs/trastuzumab-deruxtecan/>, <https://onco.cc/drugs/sacituzumab-govitecan/>, <https://onco.cc/drugs/datopotamab-deruxtecan/> ;
  onco:terms <https://onco.cc/terms/adc-sequencing/> ;
  onco:pairs <https://onco.cc/drugs/trastuzumab-deruxtecan/>, <https://onco.cc/drugs/sacituzumab-govitecan/> .