# OnCo record adc-side-effects-breast (term). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/terms/adc-side-effects-breast/>
  a schema:DefinedTerm ;
  onco:kind "term" ;
  schema:identifier "adc-side-effects-breast" ;
  schema:name "Living with an antibody-drug conjugate: diarrhoea, blood counts, eyes and lungs"@en ;
  schema:alternateName "ADC side effects"@en ;
  schema:description "The antibody-drug conjugates used in triple-negative breast cancer carry chemotherapy into the cancer but still cause chemotherapy-like effects: sacituzumab govitecan mainly low white cells and diarrhoea, datopotamab deruxtecan mouth soreness, eye problems and rarely lung inflammation, trastuzumab deruxtecan lung inflammation and sickness. Each has a threshold for ringing the 24-hour line."@en ;
  schema:url <https://onco.cc/terms/adc-side-effects-breast/> ;
  schema:dateModified "2026-09-24"^^xsd:date ;
  schema:citation <https://www.macmillan.org.uk/cancer-information-and-support/treatments-and-drugs/sacituzumab-govitecan>, <https://breastcancernow.org/about-breast-cancer/treatment/targeted-therapy/sacituzumab-govitecan-trodelvy>, <https://www.macmillan.org.uk/cancer-information-and-support/treatments-and-drugs/antibody-drug-conjugate>, <https://doi.org/10.1016/j.esmoop.2022.100554>, <https://doi.org/10.1056/NEJMoa2028485> ;
  onco:cancers <https://onco.cc/cancers/tnbc/> ;
  onco:technologies <https://onco.cc/technologies/adc/> ;
  onco:drugs <https://onco.cc/drugs/sacituzumab-govitecan/>, <https://onco.cc/drugs/datopotamab-deruxtecan/>, <https://onco.cc/drugs/trastuzumab-deruxtecan/> ;
  onco:terms <https://onco.cc/terms/neutropenia/>, <https://onco.cc/terms/ild/>, <https://onco.cc/terms/ocular-toxicity/> .