# OnCo record aff1 (target). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/targets/aff1/>
  a schema:BioChemEntity ;
  onco:kind "target" ;
  schema:identifier "aff1" ;
  schema:name "AFF1"@en ;
  schema:alternateName "ALF transcription elongation factor 1"@en, "AF4/FMR2 family member 1"@en, "AF-4"@en, "AF4"@en, "PBM1"@en, "MLLT2"@en, "AFF1" ;
  schema:description "AFF1 (AF4/FMR2 family member 1) is a gene whose normal job is to hold cell growth in check. The public catalogues list it as a tumour suppressor and a fusion partner, and it is called a cancer driver by mutation analysis of patient cohorts. Tied to Leukaemia, Non-Hodgkin lymphoma, Melanoma and 1 more."@en ;
  schema:url <https://onco.cc/targets/aff1/> ;
  schema:dateModified "2026-09-23"^^xsd:date ;
  schema:citation <https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:7135>, <https://www.uniprot.org/uniprotkb/P51825/entry>, <https://www.ncbi.nlm.nih.gov/gene/4299>, <https://www.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000172493> ;
  onco:tag "cancer-genes-wave" ;
  onco:targetClass "tumor-suppressor" ;
  schema:sameAs <https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:7135>, <https://www.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000172493>, <https://www.uniprot.org/uniprotkb/P51825/entry>, <https://www.ncbi.nlm.nih.gov/gene/4299> ;
  onco:related <https://onco.cc/collections/open-targets/>, <https://onco.cc/collections/intogen/> ;
  onco:cancers <https://onco.cc/cancers/leukaemia/>, <https://onco.cc/cancers/non-hodgkin-lymphoma/>, <https://onco.cc/cancers/melanoma/>, <https://onco.cc/cancers/all-leukemia/> .