# OnCo record agile (trial). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/trials/agile/>
  a schema:MedicalTrial ;
  onco:kind "trial" ;
  schema:identifier "agile", "NCT03173248" ;
  schema:name "AGILE"@en ;
  schema:description "In IDH1-mutated AML, adding ivosidenib to azacitidine tripled survival, one of the largest effects ever seen in a randomised AML trial."@en ;
  schema:url <https://onco.cc/trials/agile/> ;
  schema:dateModified "2026-09-07"^^xsd:date ;
  schema:citation <https://clinicaltrials.gov/study/NCT03173248>, <https://www.nejm.org/doi/full/10.1056/NEJMoa2117344> ;
  onco:status "positive" ;
  onco:phase "3" ;
  schema:startDate "2017-06-26" ;
  onco:cancers <https://onco.cc/cancers/aml/>, <https://onco.cc/cancers/aml-idh/> ;
  onco:technologies <https://onco.cc/technologies/epigenetic-drugs/>, <https://onco.cc/technologies/idh-inhibitors/>, <https://onco.cc/technologies/kinase-inhibitors/> ;
  onco:targets <https://onco.cc/targets/idh/> ;
  onco:drugs <https://onco.cc/drugs/ivosidenib/>, <https://onco.cc/drugs/azacitidine/> ;
  onco:companies <https://onco.cc/companies/servier/> ;
  onco:people <https://onco.cc/people/courtney-dinardo/> .