# OnCo record alascca (trial). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/trials/alascca/>
  a schema:MedicalTrial ;
  onco:kind "trial" ;
  schema:identifier "alascca", "NCT02647099" ;
  schema:name "ALASCCA"@en ;
  schema:description "A Nordic trial showing that three years of low-dose aspirin roughly halves recurrence in bowel cancers carrying a particular set of mutations, a biomarker-directed use of a drug that costs pennies."@en ;
  schema:url <https://onco.cc/trials/alascca/> ;
  schema:dateModified "2026-09-08"^^xsd:date ;
  schema:citation <https://clinicaltrials.gov/study/NCT02647099>, <https://doi.org/10.1056/NEJMoa2504650> ;
  onco:status "positive" ;
  onco:phase "3" ;
  schema:startDate "2016-04-07" ;
  onco:related <https://onco.cc/ideas/idea-reg-aspirin-pik3ca-implementation/> ;
  onco:cancers <https://onco.cc/cancers/colorectal/> ;
  onco:sections <https://onco.cc/fronts/nutrition-lifestyle/>, <https://onco.cc/fronts/prevention/> ;
  onco:technologies <https://onco.cc/technologies/aspirin-cancer-prevention/>, <https://onco.cc/technologies/drug-repurposing/>, <https://onco.cc/terms/ngs/> ;
  onco:targets <https://onco.cc/targets/pik3ca/> ;
  onco:drugs <https://onco.cc/drugs/aspirin/> ;
  onco:institutions <https://onco.cc/institutions/karolinska/> ;
  onco:pathways <https://onco.cc/pathways/pi3k-akt-mtor/> ;
  onco:terms <https://onco.cc/terms/germline-vs-somatic/> ;
  onco:bottlenecks <https://onco.cc/bottlenecks/b-generic-repurposing/>, <https://onco.cc/bottlenecks/b-knowledge-diffusion/> ;
  onco:keyPapers <https://onco.cc/key-papers/paper-alascca-n-engl-j-med-2025/> .