# OnCo record alkylating-agent (term). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/terms/alkylating-agent/>
  a schema:DefinedTerm ;
  onco:kind "term" ;
  schema:identifier "alkylating-agent" ;
  schema:name "Alkylating agents and antimetabolites"@en ;
  schema:alternateName "alkylating"@en, "alkylator"@en, "alkylators"@en, "alkylating agent"@en, "alkylating agents"@en, "alkylating chemotherapy"@en, "antimetabolite"@en, "antimetabolites"@en, "fluoropyrimidine"@en, "fluoropyrimidines"@en, "nucleoside analogue"@en, "purine analogue"@en, "vinca alkaloid"@en, "vinca alkaloids"@en, "vinca"@en, "5-FU"@en, "purine analogues"@en ;
  schema:description "The two oldest chemotherapy families: alkylators (cyclophosphamide, temozolomide, melphalan) glue DNA strands together so cells cannot copy them; antimetabolites (5-FU, capecitabine, methotrexate, gemcitabine) are fake building blocks that jam DNA synthesis."@en ;
  schema:url <https://onco.cc/terms/alkylating-agent/> ;
  schema:dateModified "2026-09-09"^^xsd:date ;
  schema:sameAs <https://en.wikipedia.org/wiki/Alkylating_antineoplastic_agent> ;
  schema:citation <https://en.wikipedia.org/wiki/Alkylating_antineoplastic_agent> ;
  onco:related <https://onco.cc/terms/secondary-malignancy/>, <https://onco.cc/terms/conditioning-regimen/>, <https://onco.cc/terms/lymphodepletion/>, <https://onco.cc/terms/folfox-family/> ;
  onco:sections <https://onco.cc/fronts/chemotherapy/> ;
  onco:technologies <https://onco.cc/technologies/cytotoxic-chemotherapy/> ;
  onco:drugs <https://onco.cc/drugs/cyclophosphamide/>, <https://onco.cc/drugs/fluorouracil/>, <https://onco.cc/drugs/methotrexate/>, <https://onco.cc/drugs/gemcitabine/>, <https://onco.cc/drugs/temozolomide/>, <https://onco.cc/drugs/melphalan/> .