# OnCo record alta-1l (trial). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/trials/alta-1l/>
  a schema:MedicalTrial ;
  onco:kind "trial" ;
  schema:identifier "alta-1l", "NCT02737501" ;
  schema:name "ALTA-1L"@en ;
  schema:description "ALTA-1L showed that brigatinib more than doubled the time ALK-positive lung cancer stayed under control compared with crizotinib, with strong activity against brain metastases."@en ;
  schema:url <https://onco.cc/trials/alta-1l/> ;
  schema:dateModified "2026-09-17"^^xsd:date ;
  schema:citation <https://clinicaltrials.gov/study/NCT02737501>, <https://doi.org/10.1056/NEJMoa1810171>, <https://doi.org/10.1016/j.jtho.2021.07.035> ;
  onco:status "positive" ;
  onco:phase "3" ;
  onco:cancers <https://onco.cc/cancers/nsclc/>, <https://onco.cc/cancers/alk-positive-nsclc/> ;
  onco:technologies <https://onco.cc/technologies/kinase-inhibitors/> ;
  onco:targets <https://onco.cc/targets/alk/> ;
  onco:drugs <https://onco.cc/drugs/brigatinib/>, <https://onco.cc/drugs/crizotinib/> ;
  onco:companies <https://onco.cc/companies/takeda/> ;
  onco:terms <https://onco.cc/terms/brain-metastases/> ;
  onco:people <https://onco.cc/people/ross-camidge/> .