# OnCo record alta (trial). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/trials/alta/>
  a schema:MedicalTrial ;
  onco:kind "trial" ;
  schema:identifier "alta", "NCT02094573" ;
  schema:name "ALTA"@en ;
  schema:alternateName "ALK in Lung Cancer Trial of AP26113"@en, "AP26113-13-201"@en ;
  schema:description "ALTA tested two doses of brigatinib in ALK-positive lung cancer that had progressed on crizotinib; the higher dose, started after a lower-dose first week, gave more responses and longer control, including in the brain."@en ;
  schema:url <https://onco.cc/trials/alta/> ;
  schema:dateModified "2026-09-24"^^xsd:date ;
  schema:citation <https://clinicaltrials.gov/study/NCT02094573>, <https://doi.org/10.1200/JCO.2016.71.5904>, <https://doi.org/10.1200/JCO.2017.77.5841> ;
  onco:status "completed" ;
  onco:phase "2" ;
  onco:related <https://onco.cc/trials/alta-1l/> ;
  onco:cancers <https://onco.cc/cancers/nsclc/>, <https://onco.cc/cancers/alk-positive-nsclc/> ;
  onco:technologies <https://onco.cc/technologies/kinase-inhibitors/> ;
  onco:targets <https://onco.cc/targets/alk/> ;
  onco:drugs <https://onco.cc/drugs/brigatinib/> ;
  onco:companies <https://onco.cc/companies/takeda/> ;
  onco:terms <https://onco.cc/terms/brain-metastases/> ;
  onco:people <https://onco.cc/people/kim-dong-wan/>, <https://onco.cc/people/ross-camidge/> ;
  onco:keyPapers <https://onco.cc/key-papers/paper-alta-jco-2017/> .