# OnCo record alteplase (drug). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/drugs/alteplase/>
  a schema:Drug ;
  onco:kind "drug" ;
  schema:identifier "alteplase" ;
  schema:name "Alteplase"@en ;
  schema:alternateName "tPA"@en, "Cathflo"@en, "Actilyse"@en, "Activase / Cathflo Activase" ;
  schema:description "Alteplase is a clot-dissolving medicine. In cancer care its common use is a small dose left inside a port or central line that has stopped working because of a clot, to get blood flowing through it again."@en ;
  schema:url <https://onco.cc/drugs/alteplase/> ;
  schema:dateModified "2026-11-11"^^xsd:date ;
  schema:sameAs <https://en.wikipedia.org/wiki/Alteplase> ;
  schema:citation <https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=91ecdef2-95ff-42dd-a31c-c8a09cab3ad9>, <https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=c669f77c-fa48-478b-a14b-80b20a0139c2>, <https://doi.org/10.1002/14651858.CD007119.pub2> ;
  onco:status "approved" ;
  onco:tag "supportive", "generic", "supportive-care-gaps-2026-11" ;
  onco:modality "Thrombolytic (recombinant tissue plasminogen activator)" ;
  onco:approval "US 1987: Activase: acute ischaemic stroke, acute myocardial infarction and acute massive pulmonary embolism. Cathflo Activase: restoration of function to central venous access devices" ;
  onco:related <https://onco.cc/drugs/urokinase/> ;
  onco:technologies <https://onco.cc/technologies/picc-lines/>, <https://onco.cc/technologies/implanted-ports/>, <https://onco.cc/technologies/infusion-devices-vascular-access/> ;
  onco:terms <https://onco.cc/terms/central-venous-access/> .