# OnCo record aminolevulinic-acid (drug). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/drugs/aminolevulinic-acid/>
  a schema:Drug ;
  onco:kind "drug" ;
  schema:identifier "aminolevulinic-acid" ;
  schema:name "Aminolevulinic acid (topical, for photodynamic therapy)"@en ;
  schema:alternateName "5-ALA"@en, "ALA HCl"@en, "Levulan Kerastick / Ameluz" ;
  schema:description "Aminolevulinic acid is painted on sun-damaged skin and then activated with a lamp, destroying actinic keratoses before they can become skin cancer; in Europe the gel is also approved for superficial basal cell carcinoma."@en ;
  schema:url <https://onco.cc/drugs/aminolevulinic-acid/> ;
  schema:dateModified "2026-09-10"^^xsd:date ;
  schema:sameAs <https://en.wikipedia.org/wiki/Aminolevulinic_acid> ;
  schema:citation <https://dailymed.nlm.nih.gov/dailymed/search.cfm?labeltype=all&query=aminolevulinic%20acid>, <https://www.cancer.gov/about-cancer/treatment/drugs/aminolevulinicacid>, <https://www.ema.europa.eu/en/medicines/human/EPAR/ameluz>, <https://doi.org/10.1016/j.jid.2017.09.033>, <https://www.cancerresearchuk.org/about-cancer/skin-cancer/treatment/photodynamic-therapy> ;
  onco:status "approved" ;
  onco:tag "nci-list", "prevention" ;
  onco:modality "Topical porphyrin precursor for photodynamic therapy" ;
  onco:approval "US 1999: Actinic keratoses of the face and scalp with blue-light photodynamic therapy (Levulan Kerastick)", "US 2016: Mild to moderate actinic keratosis of face and scalp with red-light PDT (Ameluz)", "EU 2011: Actinic keratosis; superficial and nodular basal cell carcinoma added 2017 (Ameluz)" ;
  onco:cancers <https://onco.cc/cancers/cutaneous-scc/>, <https://onco.cc/cancers/basal-cell-carcinoma/>, <https://onco.cc/cancers/skin-cancer/> ;
  onco:technologies <https://onco.cc/technologies/precancer-ablation/> ;
  onco:companies <https://onco.cc/companies/biofrontera/>, <https://onco.cc/companies/sun-pharma/>, <https://onco.cc/companies/photonamic/> ;
  onco:terms <https://onco.cc/terms/topical-and-destructive-treatment-bcc/> ;
  onco:trials <https://onco.cc/trials/nct07225621/>, <https://onco.cc/trials/nct05736406/> .