# OnCo record aminopterin (drug). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/drugs/aminopterin/>
  a schema:Drug ;
  onco:kind "drug" ;
  schema:identifier "aminopterin" ;
  schema:name "Aminopterin"@en ;
  schema:alternateName "4-aminopteroylglutamic acid"@en ;
  schema:description "Aminopterin was the first drug to send childhood leukaemia into remission. In 1948 Sidney Farber reported temporary remissions in children with acute leukaemia, the birth of cancer chemotherapy; its safer cousin methotrexate replaced it within a decade."@en ;
  schema:url <https://onco.cc/drugs/aminopterin/> ;
  schema:dateModified "2026-09-17"^^xsd:date ;
  schema:sameAs <https://en.wikipedia.org/wiki/Aminopterin> ;
  schema:citation <https://en.wikipedia.org/wiki/Aminopterin> ;
  onco:status "historic" ;
  onco:tag "subtype-drugs-wave" ;
  onco:modality "Antifolate (historic)" ;
  onco:related <https://onco.cc/drugs/methotrexate/> ;
  onco:cancers <https://onco.cc/cancers/all-leukemia/>, <https://onco.cc/cancers/all-paediatric-standard-risk/>, <https://onco.cc/cancers/aml/> ;
  onco:technologies <https://onco.cc/technologies/cytotoxic-chemotherapy/> ;
  onco:targets <https://onco.cc/targets/dhfr/> .