# OnCo record ampullary (cancer). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/cancers/ampullary/>
  a schema:MedicalCondition ;
  onco:kind "cancer" ;
  schema:identifier "ampullary" ;
  schema:name "Ampullary cancer (ampulla of Vater)"@en ;
  schema:alternateName "Ampulla of Vater carcinoma"@en, "Periampullary cancer"@en, "Ampullary adenocarcinoma"@en ;
  schema:description "Ampullary cancer, a biliary tract cancer, starts where the bile and pancreatic ducts empty into the small bowel. Because it blocks bile flow early it is often caught while still removable, and the Whipple operation cures a good share of patients. Tumours come in two flavours, intestinal-like and pancreas-like, and chemotherapy is increasingly chosen by which one the pathologist sees."@en ;
  schema:url <https://onco.cc/cancers/ampullary/> ;
  schema:dateModified "2026-09-10"^^xsd:date ;
  schema:sameAs <https://en.wikipedia.org/wiki/Ampullary_cancer> ;
  schema:citation <https://www.cancer.gov/types/pancreatic>, <https://www.nccn.org/guidelines/guidelines-detail?category=1&id=1520>, <https://doi.org/10.1001/jama.2012.7352> ;
  onco:tag "nci-coverage", "rare", "gastrointestinal" ;
  onco:related <https://onco.cc/cancers/pancreatic/>, <https://onco.cc/cancers/cholangiocarcinoma/>, <https://onco.cc/cancers/small-bowel/>, <https://onco.cc/cancers/colorectal/>, <https://onco.cc/cancers/gallbladder/> ;
  onco:technologies <https://onco.cc/technologies/endoscopic-resection/>, <https://onco.cc/technologies/cytotoxic-chemotherapy/>, <https://onco.cc/technologies/biliary-stenting-drainage/>, <https://onco.cc/technologies/cgp/>, <https://onco.cc/technologies/liquid-biopsy/> ;
  onco:targets <https://onco.cc/targets/kras/>, <https://onco.cc/targets/her2/>, <https://onco.cc/targets/ntrk/>, <https://onco.cc/targets/braf/> ;
  onco:drugs <https://onco.cc/drugs/folfox/>, <https://onco.cc/drugs/capox/>, <https://onco.cc/drugs/gemcitabine/>, <https://onco.cc/drugs/folfirinox/>, <https://onco.cc/drugs/gemcitabine-nab-paclitaxel/>, <https://onco.cc/drugs/pembrolizumab/> ;
  onco:pathways <https://onco.cc/pathways/wnt/>, <https://onco.cc/pathways/ras-mapk/>, <https://onco.cc/pathways/p53-cell-cycle/> ;
  onco:terms <https://onco.cc/terms/whipple/>, <https://onco.cc/terms/obstructive-jaundice/>, <https://onco.cc/terms/ca19-9/>, <https://onco.cc/terms/hereditary-cancer-syndromes/>, <https://onco.cc/terms/endoscopy/> ;
  onco:bottlenecks <https://onco.cc/bottlenecks/b-rare-cancers/>, <https://onco.cc/bottlenecks/b-trial-enrolment/> ;
  onco:keyPapers <https://onco.cc/key-papers/paper-neoptolemos-jama/> ;
  onco:pipeline <https://onco.cc/drugs/folfirinox/>, <https://onco.cc/drugs/pembrolizumab/>, <https://onco.cc/drugs/signatera/> ;
  onco:standardOfCare <https://onco.cc/technologies/endoscopic-resection/>, <https://onco.cc/terms/endoscopy/>, <https://onco.cc/terms/whipple/>, <https://onco.cc/technologies/biliary-stenting-drainage/>, <https://onco.cc/terms/lymphadenectomy/>, <https://onco.cc/drugs/folfox/>, <https://onco.cc/drugs/capox/>, <https://onco.cc/drugs/gemcitabine/>, <https://onco.cc/drugs/folfirinox/>, <https://onco.cc/trials/espac-3/>, <https://onco.cc/drugs/folfox/>, <https://onco.cc/drugs/gemcitabine-nab-paclitaxel/>, <https://onco.cc/drugs/pembrolizumab/>, <https://onco.cc/drugs/dabrafenib-trametinib/>, <https://onco.cc/drugs/larotrectinib/> .