# OnCo record amx-818 (drug). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/drugs/amx-818/>
  a schema:Drug ;
  onco:kind "drug" ;
  schema:identifier "amx-818" ;
  schema:name "VIR-5818"@en ;
  schema:alternateName "AMX-818"@en, "SAR446309"@en ;
  schema:description "VIR-5818 is an experimental masked T-cell engager from Amunix Pharmaceuticals, in phase 1 trials for HER2-expressing locally advanced or metastatic solid tumours."@en ;
  schema:url <https://onco.cc/drugs/amx-818/> ;
  schema:dateModified "2026-11-03"^^xsd:date ;
  schema:citation <https://clinicaltrials.gov/api/v2/studies/NCT05356741>, <https://www.sec.gov/Archives/edgar/data/1706431/000162828024039948/vir-20240906.htm>, <https://www.sec.gov/Archives/edgar/data/1706431/000162828026053351/a20260805-q2ex991earningsr.htm>, <https://clinicaltrials.gov/search?intr=AMX-818> ;
  onco:status "phase-1" ;
  onco:tag "pipeline", "ctgov-ingest" ;
  onco:modality "Masked T-cell engager (PRO-XTEN dual-masked TCE)" ;
  onco:cancers <https://onco.cc/cancers/metastatic-cancer/> ;
  onco:targets <https://onco.cc/targets/her2/> ;
  onco:companies <https://onco.cc/companies/amunix-pharmaceuticals/>, <https://onco.cc/companies/sanofi/>, <https://onco.cc/companies/merck-kgaa/> ;
  onco:trials <https://onco.cc/trials/nct05356741/> .