# OnCo record anal-hsil-precursor (cancer). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/cancers/anal-hsil-precursor/>
  a schema:MedicalCondition ;
  onco:kind "cancer" ;
  schema:identifier "anal-hsil-precursor" ;
  schema:name "Anal high-grade squamous intraepithelial lesions (precursor)"@en ;
  schema:alternateName "Anal HSIL"@en, "High-grade anal intraepithelial neoplasia"@en, "AIN 2 to 3"@en, "Anal dysplasia"@en, "Anal precancer"@en ;
  schema:description "Anal high-grade squamous intraepithelial lesions are the HPV-driven precancer that anal cancer grows from, found by screening people at high risk with cytology and high-resolution anoscopy. The ANCHOR trial showed that treating these lesions, mostly by ablation in the clinic, cuts the number that become anal cancer, so screening and treatment are now recommended for people living with HIV."@en ;
  schema:url <https://onco.cc/cancers/anal-hsil-precursor/> ;
  schema:dateModified "2026-09-18"^^xsd:date ;
  schema:sameAs <https://en.wikipedia.org/wiki/Anal_cancer> ;
  schema:citation <https://doi.org/10.1056/NEJMoa2201048>, <https://doi.org/10.1002/ijc.34850>, <https://en.wikipedia.org/wiki/Anal_cancer> ;
  onco:tag "subtype-page", "gastrointestinal" ;
  onco:related <https://onco.cc/cancers/localised-anal-cancer/>, <https://onco.cc/cancers/metastatic-anal-cancer/>, <https://onco.cc/cancers/anal/> ;
  onco:technologies <https://onco.cc/technologies/hpv-testing/>, <https://onco.cc/technologies/precancer-ablation/>, <https://onco.cc/technologies/hpv-vaccine/>, <https://onco.cc/technologies/cthpv-dna/> ;
  onco:drugs <https://onco.cc/drugs/fluorouracil/>, <https://onco.cc/drugs/gardasil-9/> ;
  onco:terms <https://onco.cc/terms/hpv-p16/>, <https://onco.cc/terms/cin-hsil/>, <https://onco.cc/terms/hpv-status/> ;
  onco:keyPapers <https://onco.cc/key-papers/paper-anchor-anal-hsil-treatment-nejm-2022/>, <https://onco.cc/key-papers/paper-ians-anal-cancer-screening-guidelines-ijc-2024/> ;
  onco:pipeline <https://onco.cc/technologies/cthpv-dna/>, <https://onco.cc/technologies/hpv-vaccine/>, <https://onco.cc/technologies/hpv-testing/> ;
  onco:standardOfCare <https://onco.cc/technologies/hpv-testing/>, <https://onco.cc/terms/hpv-p16/>, <https://onco.cc/technologies/cthpv-dna/>, <https://onco.cc/technologies/precancer-ablation/>, <https://onco.cc/drugs/fluorouracil/>, <https://onco.cc/technologies/hpv-vaccine/>, <https://onco.cc/drugs/gardasil-9/>, <https://onco.cc/technologies/hpv-testing/>, <https://onco.cc/terms/hpv-p16/> .