# OnCo record anchor (trial). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/trials/anchor/>
  a schema:MedicalTrial ;
  onco:kind "trial" ;
  schema:identifier "anchor", "NCT02135419" ;
  schema:name "ANCHOR"@en ;
  schema:alternateName "ANCHOR study"@en, "Anal Cancer/HSIL Outcomes Research"@en, "AMC-A01"@en ;
  schema:description "ANCHOR proved for the first time that treating precancerous anal lesions in people with HIV prevents anal cancer: those whose lesions were removed or ablated were 57 percent less likely to develop cancer than those who were simply monitored, which is the evidence behind screening and treating these lesions."@en ;
  schema:url <https://onco.cc/trials/anchor/> ;
  schema:dateModified "2026-09-22"^^xsd:date ;
  schema:citation <https://clinicaltrials.gov/study/NCT02135419> ;
  onco:status "positive" ;
  onco:tag "soc-trials" ;
  onco:phase "3" ;
  onco:cancers <https://onco.cc/cancers/anal-hsil-precursor/>, <https://onco.cc/cancers/anal/> ;
  onco:technologies <https://onco.cc/technologies/active-surveillance/> ;
  onco:drugs <https://onco.cc/drugs/fluorouracil/>, <https://onco.cc/drugs/imiquimod/> ;
  onco:keyPapers <https://onco.cc/key-papers/paper-anchor-treatment-of-anal-hsil-prevents-cancer-palefsky-nejm-2022/> .