# OnCo record anthracycline-cardioprotection (technology). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/technologies/anthracycline-cardioprotection/>
  a schema:MedicalTherapy ;
  onco:kind "technology" ;
  schema:identifier "anthracycline-cardioprotection" ;
  schema:name "Protecting the heart during anthracycline treatment: dexrazoxane, beta blockers and ACE inhibitors"@en ;
  schema:description "Dexrazoxane, given with the chemotherapy, cuts clinical heart failure in adults by about four fifths in pooled trials without reducing how well the chemotherapy works. Beta blockers and blood-pressure drugs given preventively protect the ejection fraction by a point or two during treatment, and in the one trial that followed patients for two years that difference had gone."@en ;
  schema:url <https://onco.cc/technologies/anthracycline-cardioprotection/> ;
  schema:dateModified "2026-10-02"^^xsd:date ;
  schema:sameAs <https://en.wikipedia.org/wiki/Dexrazoxane> ;
  schema:citation <https://doi.org/10.1002/14651858.CD014638.pub2>, <https://doi.org/10.1093/eurheartj/ehw022>, <https://doi.org/10.1161/CIRCULATIONAHA.121.054698>, <https://doi.org/10.1093/eurheartj/ehac244> ;
  onco:status "established" ;
  onco:tag "rejuvenation", "survivorship", "evidence:moderate" ;
  onco:related <https://onco.cc/ideas/idea-moon-cardioprotection-by-default/> ;
  onco:cancers <https://onco.cc/cancers/breast-her2-positive/>, <https://onco.cc/cancers/breast-hr-positive/>, <https://onco.cc/cancers/dlbcl/>, <https://onco.cc/cancers/sarcoma/>, <https://onco.cc/cancers/all-leukemia/> ;
  onco:sections <https://onco.cc/fronts/rejuvenation/>, <https://onco.cc/fronts/supportive-care/>, <https://onco.cc/fronts/chemotherapy/> ;
  onco:technologies <https://onco.cc/technologies/cardio-oncology/>, <https://onco.cc/technologies/cardiotoxicity-surveillance-recovery/>, <https://onco.cc/technologies/cardiac-biomarker-monitoring/> ;
  onco:drugs <https://onco.cc/drugs/dexrazoxane/>, <https://onco.cc/drugs/doxorubicin/>, <https://onco.cc/drugs/epirubicin/>, <https://onco.cc/drugs/trastuzumab/>, <https://onco.cc/drugs/pegylated-liposomal-doxorubicin/> ;
  onco:terms <https://onco.cc/terms/trastuzumab-cardiotoxicity/>, <https://onco.cc/terms/late-effects/> ;
  onco:bottlenecks <https://onco.cc/bottlenecks/b-toxicity-qol/> .