# OnCo record antigen-presentation-immunoediting (pathway). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix owl: <http://www.w3.org/2002/07/owl#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/pathways/antigen-presentation-immunoediting/>
  a schema:BioChemEntity ;
  onco:kind "pathway" ;
  schema:identifier "antigen-presentation-immunoediting" ;
  schema:name "Antigen presentation & immune editing"@en ;
  schema:description "How the immune system sees cancer, and how cancer learns to hide. Tumours display fragments of their proteins on MHC molecules; T cells kill the ones they recognise; the survivors are the ones that stopped showing fragments or switched on brakes."@en ;
  schema:url <https://onco.cc/pathways/antigen-presentation-immunoediting/> ;
  schema:dateModified "2026-09-08"^^xsd:date ;
  schema:sameAs <https://en.wikipedia.org/wiki/Immunoediting> ;
  owl:sameAs <http://www.wikidata.org/entity/Q18351145> ;
  schema:citation <https://doi.org/10.1126/science.1203486>, <https://doi.org/10.1056/NEJMoa1604958> ;
  onco:tag "mechanism" ;
  onco:cancers <https://onco.cc/cancers/tnbc/>, <https://onco.cc/cancers/non-hodgkin-lymphoma/> ;
  onco:technologies <https://onco.cc/technologies/neoantigen-mrna-vaccine/>, <https://onco.cc/technologies/tcr-t/>, <https://onco.cc/technologies/t-cell-engager/>, <https://onco.cc/technologies/car-t/>, <https://onco.cc/technologies/car-nk-macrophage/>, <https://onco.cc/technologies/checkpoint-inhibitor/> ;
  onco:targets <https://onco.cc/targets/pd1/>, <https://onco.cc/targets/pdl1/>, <https://onco.cc/targets/cd3/>, <https://onco.cc/targets/gp100/>, <https://onco.cc/targets/mage-a4/>, <https://onco.cc/targets/prame/>, <https://onco.cc/targets/hla-a/> ;
  onco:institutions <https://onco.cc/institutions/wustl-siteman/>, <https://onco.cc/institutions/mskcc/>, <https://onco.cc/institutions/nci/>, <https://onco.cc/institutions/johns-hopkins/> ;
  onco:pathways <https://onco.cc/pathways/pd1-checkpoint/>, <https://onco.cc/pathways/cgas-sting/>, <https://onco.cc/pathways/jak-stat/> ;
  onco:terms <https://onco.cc/terms/neoantigen/>, <https://onco.cc/terms/hla-a02-restriction/>, <https://onco.cc/terms/tmb/>, <https://onco.cc/terms/cold-vs-hot/>, <https://onco.cc/terms/avoiding-immune-destruction/> ;
  onco:keyPapers <https://onco.cc/key-papers/paper-zaretsky-n-engl-j-med/> .