# OnCo record apalutamide (drug). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix owl: <http://www.w3.org/2002/07/owl#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/drugs/apalutamide/>
  a schema:Drug ;
  onco:kind "drug" ;
  schema:identifier "apalutamide" ;
  schema:name "Apalutamide"@en ;
  schema:description "An AR blocker approved for prostate cancer that has spread and for high-risk disease before it shows on scans."@en ;
  schema:url <https://onco.cc/drugs/apalutamide/> ;
  schema:dateModified "2026-09-06"^^xsd:date ;
  schema:sameAs <https://en.wikipedia.org/wiki/Apalutamide> ;
  owl:sameAs <http://www.wikidata.org/entity/Q21098975> ;
  schema:citation <https://dailymed.nlm.nih.gov/dailymed/search.cfm?query=Apalutamide>, <https://www.nice.org.uk/guidance/ta741>, <https://www.nice.org.uk/guidance/ta740> ;
  onco:status "approved" ;
  onco:modality "Small-molecule AR antagonist" ;
  schema:alternateName "Erleada" ;
  onco:approval "US 2018: Non-metastatic CRPC (SPARTAN)", "US 2019: mHSPC (TITAN)" ;
  onco:cancers <https://onco.cc/cancers/prostate/>, <https://onco.cc/cancers/prostate-nmcrpc/>, <https://onco.cc/cancers/prostate-mhspc/>, <https://onco.cc/cancers/salivary-duct-carcinoma/> ;
  onco:technologies <https://onco.cc/technologies/androgen-deprivation/> ;
  onco:targets <https://onco.cc/targets/androgen-receptor/> ;
  onco:companies <https://onco.cc/companies/johnson-johnson/> ;
  onco:pathways <https://onco.cc/pathways/ar-signaling/> ;
  onco:terms <https://onco.cc/terms/mcrpc-mhspc/>, <https://onco.cc/terms/prostate-uk-drug-approvals/> ;
  onco:trials <https://onco.cc/trials/nct05884398/>, <https://onco.cc/trials/nct07611110/>, <https://onco.cc/trials/nct02489318/>, <https://onco.cc/trials/nct05422911/>, <https://onco.cc/trials/nct05367440/>, <https://onco.cc/trials/nct07745361/>, <https://onco.cc/trials/nct04557059/>, <https://onco.cc/trials/nct02257736/>, <https://onco.cc/trials/nct03767244/>, <https://onco.cc/trials/nct02531516/>, <https://onco.cc/trials/nct01946204/>, <https://onco.cc/trials/nct04325828/> .