# OnCo record apl (cancer). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/cancers/apl/>
  a schema:MedicalCondition ;
  onco:kind "cancer" ;
  schema:identifier "apl" ;
  schema:name "Acute promyelocytic leukaemia"@en ;
  schema:alternateName "APL"@en, "AML-M3"@en, "PML::RARA acute leukaemia"@en, "Promyelocytic leukaemia"@en ;
  schema:description "Acute promyelocytic leukaemia is caused by a single fused gene that freezes blood cells at an immature stage and triggers dangerous bleeding. Two non-chemotherapy drugs, a vitamin A derivative and arsenic trioxide, make the cells mature and cure more than nine in ten patients."@en ;
  schema:url <https://onco.cc/cancers/apl/> ;
  schema:dateModified "2026-09-17"^^xsd:date ;
  schema:sameAs <https://en.wikipedia.org/wiki/Acute_promyelocytic_leukemia> ;
  schema:citation <https://en.wikipedia.org/wiki/Acute_promyelocytic_leukemia>, <https://www.nccn.org/guidelines/guidelines-detail?category=1&id=1411> ;
  onco:tag "subtype-page" ;
  onco:technologies <https://onco.cc/technologies/cytogenetics-fish/>, <https://onco.cc/technologies/transfusion-support/> ;
  onco:targets <https://onco.cc/targets/rara/> ;
  onco:terms <https://onco.cc/terms/differentiation-syndrome/>, <https://onco.cc/terms/mrd/> ;
  onco:pipeline <https://onco.cc/drugs/arsenic-trioxide/>, <https://onco.cc/drugs/tretinoin-atra/> ;
  onco:standardOfCare <https://onco.cc/drugs/tretinoin-atra/>, <https://onco.cc/technologies/transfusion-support/>, <https://onco.cc/drugs/tretinoin-atra/>, <https://onco.cc/drugs/arsenic-trioxide/>, <https://onco.cc/drugs/dexamethasone/>, <https://onco.cc/drugs/tretinoin-atra/>, <https://onco.cc/drugs/arsenic-trioxide/>, <https://onco.cc/drugs/idarubicin/>, <https://onco.cc/drugs/gemtuzumab-ozogamicin/>, <https://onco.cc/drugs/arsenic-trioxide/>, <https://onco.cc/technologies/autologous-stem-cell-transplant/>, <https://onco.cc/technologies/allogeneic-hsct/> .