# OnCo record apl0406 (trial). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/trials/apl0406/>
  a schema:MedicalTrial ;
  onco:kind "trial" ;
  schema:identifier "apl0406", "NCT00482833" ;
  schema:name "APL0406"@en ;
  schema:alternateName "GIMEMA-AMLSG-SAL APL0406"@en ;
  schema:description "APL0406 showed that acute promyelocytic leukaemia can be cured without conventional chemotherapy: retinoic acid plus arsenic trioxide did at least as well as, and in fact better than, the standard chemotherapy-based treatment."@en ;
  schema:url <https://onco.cc/trials/apl0406/> ;
  schema:dateModified "2026-09-17"^^xsd:date ;
  schema:citation <https://clinicaltrials.gov/study/NCT00482833> ;
  onco:status "positive" ;
  onco:tag "subtype-trials" ;
  onco:phase "3" ;
  onco:cancers <https://onco.cc/cancers/apl/>, <https://onco.cc/cancers/aml/> ;
  onco:drugs <https://onco.cc/drugs/tretinoin-atra/>, <https://onco.cc/drugs/arsenic-trioxide/> ;
  onco:people <https://onco.cc/people/francesco-lo-coco/> ;
  onco:keyPapers <https://onco.cc/key-papers/paper-apl0406-lo-coco-nejm-2013/> .